Kaitlin McCreery
Assistant Professor, Department of Electrical and Biomedical Engineering
PRONOUNS she/her
- Ph.D. in Biomedical Engineering, University of Colorado Boulder
- M.S. in Mechanical Engineering, University of Colorado Boulder
- B.A. in Physics, Duke University
Department of Electrical and Biomedical Engineering
BIO
Kaitlin McCreery is an Assistant Professor in the Department of Electrical and Biomedical Engineering at ¶¶Òõ̽̽. She obtained a B.A. degree in Physics from Duke University and a M.S. degree in Mechanical Engineering at the University of Colorado Boulder. Subsequently, she completed a Ph.D. in Biomedical Engineering at the University of Colorado Boulder with a certificate in Interdisciplinary Quantitative Biology from the BioFrontiers Institute, studying biomechanics and mechanobiology with Dr. Corey Neu. She completed a postdoctoral fellowship in nuclear mechanobiology and mechanotransduction with Dr. Sara Wickström in the Department of Cell and Tissue Dynamics at the Max Planck Institute for Molecular Biomedicine in Münster, Germany. Her training dove deep into scale-bridging technologies to reveal structure-function relationships in mechanobiology utilizing advanced microscopy, atomic force microscopy and next-generation sequencing and extending to in vitro and ex vivo stem cell and connective tissue models.
The research in the McCreery Lab integrates biomechanics, nuclear mechanobiology, and tissue engineering to explore how physical forces and biochemical signals guide cell states, fates, and tissue disease states including degeneration and fibrosis. By combining cutting-edge techniques in atomic force microscopy, multi-omics data integration, and tissue engineering, her lab’s goal is to develop innovative cell-manufactured scaffolds and regenerative therapies that harmoniously blend stem cells with native tissues.
Dr. McCreery will begin her appointment with the EBE Department in January 2025.
Courses
EBE/ME 5990: Engineering Mechanobiology
Area(s) of expertise
Biomechanics and Mechanobiology, Biophysics, Bioinformatics, Bioengineering, Atomic Force Microscopy, Interface Tissue Mechanics, Stem Cell Mechanotransduction
Bio
Kaitlin McCreery is an Assistant Professor in the Department of Electrical and Biomedical Engineering at ¶¶Òõ̽̽. She obtained a B.A. degree in Physics from Duke University and a M.S. degree in Mechanical Engineering at the University of Colorado Boulder. Subsequently, she completed a Ph.D. in Biomedical Engineering at the University of Colorado Boulder with a certificate in Interdisciplinary Quantitative Biology from the BioFrontiers Institute, studying biomechanics and mechanobiology with Dr. Corey Neu. She completed a postdoctoral fellowship in nuclear mechanobiology and mechanotransduction with Dr. Sara Wickström in the Department of Cell and Tissue Dynamics at the Max Planck Institute for Molecular Biomedicine in Münster, Germany. Her training dove deep into scale-bridging technologies to reveal structure-function relationships in mechanobiology utilizing advanced microscopy, atomic force microscopy and next-generation sequencing and extending to in vitro and ex vivo stem cell and connective tissue models.
The research in the McCreery Lab integrates biomechanics, nuclear mechanobiology, and tissue engineering to explore how physical forces and biochemical signals guide cell states, fates, and tissue disease states including degeneration and fibrosis. By combining cutting-edge techniques in atomic force microscopy, multi-omics data integration, and tissue engineering, her lab’s goal is to develop innovative cell-manufactured scaffolds and regenerative therapies that harmoniously blend stem cells with native tissues.
Dr. McCreery will begin her appointment with the EBE Department in January 2025.
Courses
EBE/ME 5990: Engineering Mechanobiology
Areas of Expertise
Biomechanics and Mechanobiology, Biophysics, Bioinformatics, Bioengineering, Atomic Force Microscopy, Interface Tissue Mechanics, Stem Cell Mechanotransduction
Selected Publications
- McCreery, K.P., Stubb, A.S., Lee, H., Stephens R., Cook A., Kruse, K., Vuoristo S., Miroshnikova Y.A, Wickström, S.A. Mechano-osmotic signals control chromatin state and exit from pluripotency. Nature Cell Biology, In Press.
- McCreery, K.P., Luetkemeyer, C.M., Calve, S., Neu, C.P. (2023) Hyperelastic characterization reveals proteoglycans drive the nanoscale strain-stiffening response in hyaline cartilage. Journal of Biomechanics, 146, 111397.
- Barthold, J.E., McCreery, K.P., Bellerjeau, C., Bryant, S.J., Whiting, G.L., Neu, C.P. (2022). Particulate ECM biomaterial ink is 3D Printed and naturally crosslinked to form structurally-layered and lubricated cartilage tissue mimics. Biofabrication 14(2), 025021.
- Lipp, S.N., Jacobson, K.R., Colling, H.A., Tuttle, T.G., Miles, D.T., McCreery, K.P., Calve, S. (2023). Mechanical loading is required for initiation of extracellular matrix deposition at the developing murine myotendinous junction. Matrix Biology 116 28—48.
- McCreery, K.P., Xu, X., Scott, A.K., Fairjrial, A.K., Calve, S., Ding, X., Neu, C.P. (2021) Nuclear stiffness decreases with disruption of the extracellular matrix in living tissues. Small 17(6).
- McCreery, K.P., Calve, S., Neu, C.P. (2020) Ontogeny Informs Regeneration: explant models to investigate the role of the extracellular matrix in cartilage tissue assembly and development. Connective Tissue Research 61(3-4).
- Lynch, M.E., Neu, C.P., Seelbinder, B., McCreery, K.P. (2020). The Role of Mechanobiology in Cancer Metastasis. Mechanobiology 65-78.